Product Overview
| Target Name | Survivin |
|---|---|
| UniProt ID | O15392 |
| Alternative Names | API4; EPR-1 |
Applications and Recommended Dilutions
| Tested Application | Immunohistochemistry (Frozen),Super Resolution Microscopy |
|---|---|
| Recommended Dilutions | IHC-Fr - 0.2µL/mL, Super Resolution Microscopy - 0.07µL/mL |
Specificity and Sensitivity
| Epitope | Binds to native Human PSD95 Corresponding to AA 68 to 251 |
|---|---|
| Species Reactivity | Human,Mouse,Rat |
Sizes and Weights
| Nanobody Size (µL) | 100 |
|---|---|
| Molecular Weight (kDa) | 16 |
Storage Conditions
| Buffer Composition | Supplied in PBS (pH 7.5), 150 mM NaCl |
|---|---|
| Short-Term Storage | 4°C up to 2 months. |
| Long-Term Storage | -20°C up to 36 months. Do not aliquot the antibody |
Source and Purification
| Purification Method | Affinity Purified |
|---|---|
| Nanobody Concentration (mg/ml ±10%) | 0.7 |
Additional Information
| Clone Number | ZIAB6-06 |
|---|---|
| SKU / Catalog | Nab61100-100 |
| Product Name | Survivin (pThr34)Nanobody (Human) [ZIAB6-06] - Unconjugated Cat# Nab61100-100 |
| EntrezGene Database Link | 332 |
| Research Areas | Oncology, Neuroscience, Immunology, ImmunoOncology |
| Modification | (pThr34) |
| Product Type | Recombinant Monoclonal Single Domain Antibody |
| Conjugation Type | Unconjugated |
| Target Description | Survivin is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |